Table 1.
West Nile virus at a glance.
Family | Flaviviridae (includes YFV, Dengue, TBE, JEV, MVE) |
Biology | arboviral CNS pathogen |
Host range | diverse, including many mammals and birds |
Vector | Culex spp. mosquitoes |
Epidemiology | First isolated in Uganda (1938); Re-emergent in USA (1999) |
Genome | 11 kb (+) single stranded RNA |
Structure | enveloped icosahedral nucleocapsid ~50 nm diameter sphere |
Tissue tropism | neurotropic |
Treatment | no specific agents |
Prevention | no human vaccines |