(Top) Antigen stimulation rate, a(t), given by (5.2). (Bottom) Time evolution of effector and iTreg populations, E(t) and R(t), from system (5.1). The system produces an effector response against the second and third jumps beginning on days 120 and 320, but ignores the two smaller jumps beginning on days 20 and 220. The effector cell concentrations, E(t), peak on days 129.6 and 134.6.