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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: J Endocrinol. 2010 Jul 30;207(1):67–75. doi: 10.1677/JOE-10-0181

Figure 5. Wnt pathway in renal FGF23 signaling.

Figure 5

Figure 5

a) Strong p-β-catenin signaling was detected in the glomeruli of all animals (green), separate from the DCT, which was demarcated using anti-NCC IF (red). b) p-β-catenin signaling was tested by IF in vehicle and FGF23-injected mice at 10 min following injection. p-β-catenin signaling was not detected in the vehicle injected animals. In the FGF23-injected animals, p-β-catenin (red) was detected in the distal tubule, co-localized with Klotho (green). This activity did not co-localize with Npt2a in the renal PT (right column).