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. Author manuscript; available in PMC: 2011 Mar 8.
Published in final edited form as: JAMA. 2009 May 20;301(19):2005–2015. doi: 10.1001/jama.2009.682

Table 4.

Insomnia Severity Index means and standard errors (SE) and percentages of treatment responders and remitters

Acute treatment
Extended treatment
Follow-up
Pre
Post-I
Post-II
6-months
Condition Mean
(SE)
Mean
(SE)
Change
(95% CI)
d Condition Mean
(SE)
Change
(95% CI)
d Mean
(SE)
Change
(95% CI)
d
ISI (patient) raw score
CBT 17.26
(0.47)
8.94
(0.48)
−8.3
(−9.4, −7.2)
−2.00 CBT 8.68
(0.73)
−1.0
(−2.5, 0.6)
−0.23 8.94
(0.71)
0.3
(−1.3, 1.9)
0.06
No txt 8.11
(0.75)
−0.2
(−1.8, 1.4)
−0.04 8.85
(0.69)
0.7
(−0.8, 2.3)
0.18
Combined
CBT/Med
17.55
(0.47)
8.76
(0.49)
−8.8
(−9.9, −7.7)
−2.11 CBT/
Taper
6.95
(0.74)
−0.4
(−2.0, 1.2)
−0.09 5.82
(0.74)
−1.1
(−2.8, 0.6)
−0.26
CBT/
Medprn
8.71
(0.76)
−1.4
(−3.0, 0.2)
−0.32 8.77
(0.75)
0.0
(−1.7, 1.7)
0.01

%
(n)
Condition %
(n)
OR
(95% CI)
%
(n)
OR
(95% CI)

Treatment responders (ISI reductions ≥ 8 compared to baseline ISI)
CBT -- 59.46*
(45/75)
-- CBT 62.87
(24/38)
1.23
(0.62,2.45)
62.80
(21/33)
1.00
(0.45,2.20)
No txt 55.01
(20/37)
0.76
(0.35,1.67)
57.15
(20/35)
1.09
(0.54,2.22)
Combined
CBT/Med
-- 61.11
(45/74)
-- CBT/
Taper
73.88
(27/37)
1.26
(0.44,3.49)
80.86
(24/30)
1.49
(0.62,3.61)
CBT/
Medprn
69.56
(26/37)
1.94
(0.78,4.85)
64.87
(19/29)
0.81
(0.31,1.91)

Treatment remitters (ISI < 8)
CBT 0.0 39.19
(29/75)
-- CBT 43.87
(17/38)
1.92
(0.78,4.74)
43.89
(14/33)
1.00
(0.51,1.97)
No txt 45.29
(17/37)
0.85
(0.34,2.14)
40.28
(14/35)
0.81
(0.37,1.79)
Combined
CBT/Med
0.0 44.44
(33/74)
-- CBT/
Taper
56.89
(21/37)
0.85
(0.43,1.66)
67.78
(20/30)
1.59
(0.78,3.27)
CBT/
Medprn
59.76
(22/37)
3.50
(1.53,8.04)
41.73
(12/29)
0.48
(0.25,0.93)
*

Note. These “estimated” percentages, derived from generalized linear mixed models, are adjusted for missing data and may not correspond exactly to the actual frequencies.