Table 4.
Acute treatment |
Extended treatment |
Follow-up |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Pre |
Post-I |
Post-II |
6-months |
||||||||
Condition |
Mean (SE) |
Mean (SE) |
Change (95% CI) |
d | Condition |
Mean (SE) |
Change (95% CI) |
d |
Mean (SE) |
Change (95% CI) |
d |
ISI (patient) raw score | |||||||||||
CBT | 17.26 (0.47) |
8.94 (0.48) |
−8.3 (−9.4, −7.2) |
−2.00 | CBT | 8.68 (0.73) |
−1.0 (−2.5, 0.6) |
−0.23 | 8.94 (0.71) |
0.3 (−1.3, 1.9) |
0.06 |
No txt | 8.11 (0.75) |
−0.2 (−1.8, 1.4) |
−0.04 | 8.85 (0.69) |
0.7 (−0.8, 2.3) |
0.18 | |||||
Combined CBT/Med |
17.55 (0.47) |
8.76 (0.49) |
−8.8 (−9.9, −7.7) |
−2.11 | CBT/ Taper |
6.95 (0.74) |
−0.4 (−2.0, 1.2) |
−0.09 | 5.82 (0.74) |
−1.1 (−2.8, 0.6) |
−0.26 |
CBT/ Medprn |
8.71 (0.76) |
−1.4 (−3.0, 0.2) |
−0.32 | 8.77 (0.75) |
0.0 (−1.7, 1.7) |
0.01 | |||||
% (n) |
Condition |
% (n) |
OR (95% CI) |
% (n) |
OR (95% CI) |
||||||
Treatment responders (ISI reductions ≥ 8 compared to baseline ISI) | |||||||||||
CBT | -- | 59.46* (45/75) |
-- | CBT | 62.87 (24/38) |
1.23 (0.62,2.45) |
62.80 (21/33) |
1.00 (0.45,2.20) |
|||
No txt | 55.01 (20/37) |
0.76 (0.35,1.67) |
57.15 (20/35) |
1.09 (0.54,2.22) |
|||||||
Combined CBT/Med |
-- | 61.11 (45/74) |
-- | CBT/ Taper |
73.88 (27/37) |
1.26 (0.44,3.49) |
80.86 (24/30) |
1.49 (0.62,3.61) |
|||
CBT/ Medprn |
69.56 (26/37) |
1.94 (0.78,4.85) |
64.87 (19/29) |
0.81 (0.31,1.91) |
|||||||
Treatment remitters (ISI < 8) | |||||||||||
CBT | 0.0 | 39.19 (29/75) |
-- | CBT | 43.87 (17/38) |
1.92 (0.78,4.74) |
43.89 (14/33) |
1.00 (0.51,1.97) |
|||
No txt | 45.29 (17/37) |
0.85 (0.34,2.14) |
40.28 (14/35) |
0.81 (0.37,1.79) |
|||||||
Combined CBT/Med |
0.0 | 44.44 (33/74) |
-- | CBT/ Taper |
56.89 (21/37) |
0.85 (0.43,1.66) |
67.78 (20/30) |
1.59 (0.78,3.27) |
|||
CBT/ Medprn |
59.76 (22/37) |
3.50 (1.53,8.04) |
41.73 (12/29) |
0.48 (0.25,0.93) |
Note. These “estimated” percentages, derived from generalized linear mixed models, are adjusted for missing data and may not correspond exactly to the actual frequencies.