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β-Catenin signaling is sufficient and necessary for Wnt9b progenitor target gene expression. (A-R) In situ hybridization evaluating the expression of C1qdc2 (A,B,G-I), Pla2g7 (C,D,J-L) and Tafa5 (E,F,M-O) and Uncx4.1 (P-R). A-F represent E11.5 metanephric mesenchyme cultured for 48 hours in media alone (A,C,E) or in media containing 15 mM LiCl (B,D,F). (G-R) Embryonic kidneys grown in the presence of DMSO (G,J,M,P), 5 μM IWP2 (H,K,N,Q) or 100 μM IWR1 (I,L,O,R).
