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. 2011 Apr 1;138(7):1275–1280. doi: 10.1242/dev.062158

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Fig. 4. — P30 control and Fgfr2/Frs2α^UB^−/− kidneys in situ hybridization and histological sections. (A-C) Compared with controls (A), Fgfr2/Frs2α^UB−/− mutants often have a translucent or cystic appearance (B) or frank hydronephrosis (C). (D-F) Compared with controls (D), Fgfr2 ^UB−/− kidneys (E) appear similar except that the glomeruli (concave arrowheads) are larger. By contrast, Fgfr2/Frs2α^UB−/− kidneys (F) are dysplastic with many cysts (asterisks) and have tubules filled with proteinaceous material (arrowheads). Scale bar: 0.25 cm for A-C; 150 μm for D-F.