Table 2.
Mean % antibody depletion from FVO, HB3 and 3D7 AMA1-coated plates.
| Coating antigen | Competitor antigen | Gp 1 (f3h) n = 5 | Gp 2 (hf3) n = 6 | Gp 3 (h3f) n = 4 | Gp 4 (NA mix) n = 6 | Gp5 (DiCo mix) n = 6 |
|---|---|---|---|---|---|---|
| FVO AMA1 | FVO | 98.5 (97.3 - 99.7) | 95.9 (95.1 - 96.8) | 98.2 (96.3 - 100.1) | 96.8 (95.4 - 98.2) | 97.6 (96.4 - 98.7) |
| HB3 | 93.2 (88.1 - 98.3) | 90.4 (87.0 - 93.8) | 93.2 (86.0 - 100.4) | 90.6 (87.4 - 93.9) | 91.3 (89.7 - 92.9) | |
| 3D7 | 84.5 (77.5 - 91.5) | 75.5 (74.3 - 76.7) | 76.6 (65.4 - 87.8) | 70.4 (64.7 - 76.0) | 77.0 (69.4 - 84.7) | |
| CAMP | 78.7 (73.6 - 83.7) | 70.3 (65.9 - 74.6) | 74.2 (64.4 - 84.1) | 70.3 (64.7 - 74.0) | 84.0 (82.3 - 85.8) | |
| HB3 AMA1 | FVO | 87.5 (79.0 - 96.0) | 86.0 (81.2 - 90.9) | 91.4 (89.3 - 93.6) | 86.6 (83.3 - 89.9) | 84.1 (80.6 - 87.5) |
| HB3 | 96.1 (93.6 - 98.5) | 97.5 (95.4 - 99.6) | 98.2 (98.1 - 98.4) | 96.7 (95.0 - 98.4) | 95.6 (93.7 - 97.4) | |
| 3D7 | 86.7 (82.3 - 91.0) | 84.3 (75.9 - 92.8) | 77.9 (70.5 - 85.4) | 73.7 (66.7 - 80.6) | 74.7 (70.5 - 78.9) | |
| CAMP | 76.8 (73.4 - 80.1) | 68.5 (62.7 - 74.3) | 74.4 (70.2 - 78.6) | 66.8 (60.2 - 73.3) | 81.2 (78.2 - 84.2) | |
| 3D7 AMA1 | FVO | 83.0 (75.3 - 90.8) | 91.8 (86.7 - 97.0) | 91.3 (84.8 - 97.9) | 73.2 (66.1 - 80.3) | 86.9 (84.4 - 89.4) |
| HB3 | 89.3 (85.2 - 93.4) | 95.9 (92.7 - 99.1) | 94.1 (89.2 - 99.0) | 83.6 (76.1 - 91.1) | 88.7 (86.2 - 91.2) | |
| 3D7 | 100.2 (96.8 - 103.7) | 98.2 (95.9 - 100.2) | 96.8 (94.6 - 99.0) | 95.8 (94.3 - 97.4) | 97.1 (95.2 - 99.0) | |
| CAMP | 79.5 (71.6 - 87.5) | 82.0 (77.0 - 87.1) | 85.7 (77.0 - 94.5) | 71.0 (66.5 - 75.5) | 89.2 (86.0 - 92.4) |
Values reported as mean (95% CI) per immunization group for the same competitor antigen on each coating antigen.