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How to induce cartilage regeneration. A: We created a cylindrical osteochondral defect having a diameter of 2.4-mm in the medial condyle of the FT joint. Then, we implanted a double network (DN) gel plug into a bottom of the defect. B: A schematic cross-section of the osteochondral defect into which the plug was implanted. Note that a defect having a few millimeter depth from the cartilage surface remained after surgery.
