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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Immunol. 2010 Jul 9;185(3):1650–1659. doi: 10.4049/jimmunol.0902626

Figure 4. Ki67 response and change in T-cell levels at 6-week dosing intervals.

Figure 4

We assessed the change in Ki67+ T cells from pre-rsIL-7gly levels at each time point. Basal Ki67 levels were determined by averaging three rsIL-7gly time points prior to IL-7. rsIL-7gly administration is indicated by [↓]. Central memory (CM) (red) and naïve cells (green) (A) CD4+ T cells (B) CD8+ T cells. We then determined the effect of rsIL-7gly on the absolute number of T cells over time. The fold change was determined from the basal level of each T-cell subset; CM (black) and naïve cells (grey). (C) Fold change in CD4+ T cells (D) Fold change in CD8+ T cells