. Author manuscript; available in PMC: 2011 Aug 1.

Published in final edited form as: J Immunol. 2010 Jul 9;185(3):1650–1659. doi: 10.4049/jimmunol.0902626

TABLE I. rsIL-7gly dosing regimens administered.

Rhesus macques were divided into 4 different dosing schemes over the course of these studies. Table 1 shows the number of animals, the number of rsIL-7gly doses each animal received during the study and the interval between rsIL-7gly doses. Some macaques were used in multiple studies and in each case the interval between studies was greater than 10 weeks.

Study Title	RM#	Total # of rsIL-7gly doses	Interval between doses	Days of rsIL-7gly Administration
rsIL-7gly treatment in SIVneg RMs	8 uninfected RMs	2	2 doses of rsIL-7gly at a one week interval	0,7
rsIL-7gly 2, 4 or 6 week Intervals	RM2-01	3	2 doses of rsIL-7gly at one week interval (N=6); followed by one dose at 2, 4 or 6 week intervals (N=2)	0,7 21or 35 or 49
	RM2-02
	RM2-03
	RM2-04
	RM2-05
	RM2-06
rsIL-7gly 6-week intervals	RM2-01	3	One rsIL-7gly dose every 6 weeks	0,42,84
	RM2-03
	RM2-04
Clustered rsIL-7gly Doses	RM2-05	9	3 doses of rsIL-7gly at one week intervals followed by two weeks without; repeated three times	0,7,14, 35,42,49, 70,77,84
Clustered rsIL-7gly Doses	RM2-07	9		0,7,14, 35,42,49, 70,77,84
ART controls	RM2-02	0	n/a	n/a
	RM2-06
	RM2-08
	RM2-09