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. 2011 Feb 23;8:78. doi: 10.1186/1743-422X-8-78

Figure 1.

Figure 1

The average production of HBsAb (mIU/ml) in mice immunized with different dosage of CpG DNA and recombinant expressed HBsAg or HBV commercial vaccine in four weeks. A: mice immunized with HBV vaccine and 20 μg CpG DNA; star: mice immunized with HBV vaccine and 5 μg CpG DNA; dot: mice immunized with HBsAg and 5 μg CpG DNA; square: mice immunized with HBsAg and 20 μg CpG DNA; diamond: mice immunized with HBV vaccine and 1.25 μg CpG DNA; circle: mice immunized with HBsAg and 1.25 μg CpG DNA; triangle: mice only immunized with HBV vaccine; line only: mice only immunized with HBsAg; mice injected with alum and saline solution did not produce HBsAb.