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. 2011 Feb 16;11:75. doi: 10.1186/1471-2407-11-75

Table 1.

Regimens and drug doses of control and experimental arms

Setting Treatment Arm Regimens Dose Schedule Reference
Locally advanced Control Epirubicin 75 mg/m², d 1 Every 3 weeks for 4 cycles de Matteis A, 2002
Docetaxel 80 mg/m², d 1
Experimental Epirubicin 30 mg/m², dd 1-8-15 Every 4 weeks for 3 cycles Wenzel C, 2002
Docetaxel 35 mg/m², dd 1-8-15

Metastatic, no previous anthracyclines Control Epirubicin 60 mg/m², d 1 Every 3 weeks for 6 cycles Trudeau ME, 1999
Docetaxel 75 mg/m², d 1
Experimental Epirubicin 25 mg/m², dd 1-8-15 Every 4 weeks for 6 cycles Wenzel C, 2002
Docetaxel 30 mg/m², dd 1-8-15

Metastatic, previously treated with anthracyclines Control Capecitabine 1000 mg/m², b.i.d., dd 1-14 Every 3 weeks for 6 cycles Pronk LC, 2000
Docetaxel 75 mg/m², d 1
Experimental Capecitabine 625 mg/m², b.i.d., dd 5-18 Every 4 weeks for 6 cycles Nadella P, 2002
Docetaxel 35 mg/m², dd 1-8-15