Table 1.

IC₅₀ values for doxorubicin with or without sFZD7 in human heptaoma cell lines following 72 h of drug treatment in vitro

Cell line	IC50 (μM) Doxorubicin only	IC50 (μM) Doxorubicin+sFZD7 (2 μg/ml)	Sensitivity Index
Huh7	0.10 ± 0.02	0.05 ± 0.01*	2.00
HepG2	7.42 ± 0.90	4.66 ± 0.50*	1.59

Values are expressed as mean ± SD. The chemosensitizing effects of doxorubicin in combination with sFZD7 are expressed as the sensitivity index (Mean IC₅₀ value for doxorubicin alone/Mean IC₅₀ value for doxorubicin + sFZD7). Independent T-test was used to compare the IC₅₀ values of doxorubicin alone or in combination with sFZD7; * P < 0.05 in both cell lines.