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. 2011 Mar 8;6(3):e17639. doi: 10.1371/journal.pone.0017639

Table 1. Mouse SuperArray data showing greater than 1.5 fold cell stress RNA expression changes in the spinal cord of YFP-16 mice compared with wild-type controls (*array cell refers to the location on the 3D bar chart in Fig. 1A).

Array cell* Symbol Fold change Role in cell stress
A09 Ccl4 3.26 Inflammation
C03 Cyp7a1 3.14 Oxidative or metabolic stress
A08 Ccl3 2.94 Inflammation
B04 Csf2 2.77 Inflammation
A05 Casp1 2.30 Apoptosis signalling
F06 Nfkbia 2.26 Apoptosis signalling
B11 Cyp2c29 2.23 Oxidative or metabolic stress
F01 Lta 2.18 Inflammation
A06 Casp8 2.11 Apoptosis signalling
B02 Chek2 2.07 DNA damage and repair
A01 Anxa5 1.95 Apoptosis signalling
A07 Ccl21b 1.94 Inflammation
C01 Cyp4a10 1.93 Oxidative or metabolic stress
G05 Tnfsf10 1.92 Apoptosis signalling
D05 Gpx2 1.90 Oxidative or metabolic stress
A03 Bax 1.89 Apoptosis signalling
B05 Cxcl10 1.84 Inflammation
D09 Hmox1 1.84 Oxidative or metabolic stress
B10 Cyp2b9 1.84 Oxidative or metabolic stress
F07 Nos2 1.79 Inflammation
D08 Gstm3 1.79 Oxidative or metabolic stress
B06 Cyp1a1 1.74 Oxidative or metabolic stress
F02 Mdm2 1.72 Growth arrest and senescence
C07 Egr1 1.72 Proliferation and carcinogenesis
C04 Ddit3 1.68 Growth arrest and senescence
F12 Rad50 1.67 DNA damage and repair
A02 Atm 1.66 DNA damage and repair
E11 Il1b 1.65 Inflammation
C02 Cyp4a14 1.64 Oxidative or metabolic stress
H01 Gusb 1.63 Oxidative or metabolic stress
B07 Cyp1b1 1.63 Oxidative or metabolic stress
G08 Ugt1a2 1.63 DNA damage and repair
C12 Fmo1 1.62 Oxidative or metabolic stress
A04 Bcl2l1 1.62 Apoptosis signalling
E02 Hspa4 1.60 Heat Shock
A11 Ccnd1 1.59 Proliferation and carcinogenesis
B03 Cryab 1.56 Oxidative or metabolic stress
B09 Cyp2b10 1.56 Oxidative or metabolic stress
B12 Cyp3a11 1.56 Oxidative or metabolic stress
F11 Rad23a 1.52 DNA damage and repair
G04 Tnfrsf1a 1.52 Apoptosis signalling