Figure 6. Effects of wild type and V326N peptides on polystyrene biofilms.

(A) C. albicans or S. cerevisiae expressing Als5p^WT, Als5p^V326N, or no Als5p (EV) strains were adhered to a polystyrene surface in the absence and presence of the wild-type peptide (2 ug/ml) or V326N peptide (200 ug/ml) for 1.5 h. Adherent cells were grown overnight, stained with 1% crystal violet and imaged. (B) Crystal violet quantification of binding. Peptide-treated strains with p values relative to untreated strains were determined as significant by Student's T-test (p≤0.05(*), p≤0.01(**), and p≤0.001(***)).