Table 5. Risk factors of Streptococcus suis infection on univariate analysis.
Exposure | Cases versus Hospital controls | Cases versus Community controls | ||||||
OR(1) (95%CI) | p value | OR(2) (95%CI) | p value | OR(1) (95%CI) | p value | OR(3) (95%CI) | p value | |
Occupations related to pigs | 9.68(4.13–22.67) | <0.001 | 7.51(2.85–19.82) | <0.001 | 11.50(4.31–30.65) | <0.001 | 11.01(4.03–30.12) | <0.001 |
Medical history | ||||||||
Diabetes mellitus | 3.06(0.61–15.41) | 0.175 | 0.82(0.13–5.23) | 0.830 | 2.25(0.50–10.05) | 0.288 | 3.75(0.75–18.73) | 0.107 |
Alcoholism | 2.55(1.22–5.33) | 0.013 | 1.31(0.54–3.16) | 0.547 | 2.50(1.15–5.45) | 0.021 | 1.48(0.63–3.31) | 0.381 |
Skin injuries | 7.68(4.08–14.46) | <0.001 | 8.16(3.72–17.92) | <0.001 | 22.09(7.79–62.64) | <0.001 | 22.30(7.55–65.84) | <0.001 |
Breeding pigs at home | 2.41(1.34–4.35) | 0.003 | 2.34(1.09–5.00) | 0.028 | 1.95(1.04–3.65) | 0.036 | 1.99(1.04–3.80) | 0.036 |
Any exposure to pigs/pork in the last 2 weeks | 5.66(3.38–9.49) | <0.001 | 4.69(2.43–9.07) | <0.001 | 4.51(2.55–7.97) | <0.001 | 4.16(2.30–7.52) | <0.001 |
With skin injuries | 14.72(5.36–40.42) | <0.001 | 12.16(3.74–39.50) | <0.001 | 30(7.01–128.35) | <0.001 | 26.95(6.14–118.23) | <0.001 |
Without skin injuries | 2.74(1.55–4.86) | 0.001 | 2.06(0.99–4.27) | 0.052 | 1.66(0.92–3.00) | 0.090 | 1.57(0.85–2.91) | 0.152 |
Eating any “high risk” dish in the last 2 weeks | 3.25(2.02–5.24) | <0.001 | 2.48(1.35–4.52) | 0.003 | 6.00(3.33–10.81) | <0.001 | 4.38(2.72–8.08) | <0.001 |
Ill pigs at home in the last 4 weeks (4) | 24.62(2.85–212.24) | 0.004 | 30.10(2.72–333.64) | 0.006 | - | - | - | - |
Pigs at home with S. suis serotype 2 (confirmed by PCR) (5) | 2.31(0.49–10.82) | 0.289 | 7.83(0.68–90.19) | 0.099 | - | - | - | - |
Crude OR based on logistic (hospital controls) or conditional logistic regression (community controls).
Adjusted for age, sex and rural/urban residence, using logistic regression.
Adjusted for sex (matched for age and residence), using conditional logistic regression.
Only individuals with pigs at home were analyzed. OR could not be analyzed for community controls because none of them reported ill pigs at home.
Only individuals who had pig swab samples at their houses were analyzed. OR could not be analyzed for community controls because there was no discordant pairs included in the analysis.