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. 2011 Mar 8;6(3):e17604. doi: 10.1371/journal.pone.0017604

Table 5. Risk factors of Streptococcus suis infection on univariate analysis.

Exposure Cases versus Hospital controls Cases versus Community controls
OR(1) (95%CI) p value OR(2) (95%CI) p value OR(1) (95%CI) p value OR(3) (95%CI) p value
Occupations related to pigs 9.68(4.13–22.67) <0.001 7.51(2.85–19.82) <0.001 11.50(4.31–30.65) <0.001 11.01(4.03–30.12) <0.001
Medical history
Diabetes mellitus 3.06(0.61–15.41) 0.175 0.82(0.13–5.23) 0.830 2.25(0.50–10.05) 0.288 3.75(0.75–18.73) 0.107
Alcoholism 2.55(1.22–5.33) 0.013 1.31(0.54–3.16) 0.547 2.50(1.15–5.45) 0.021 1.48(0.63–3.31) 0.381
Skin injuries 7.68(4.08–14.46) <0.001 8.16(3.72–17.92) <0.001 22.09(7.79–62.64) <0.001 22.30(7.55–65.84) <0.001
Breeding pigs at home 2.41(1.34–4.35) 0.003 2.34(1.09–5.00) 0.028 1.95(1.04–3.65) 0.036 1.99(1.04–3.80) 0.036
Any exposure to pigs/pork in the last 2 weeks 5.66(3.38–9.49) <0.001 4.69(2.43–9.07) <0.001 4.51(2.55–7.97) <0.001 4.16(2.30–7.52) <0.001
With skin injuries 14.72(5.36–40.42) <0.001 12.16(3.74–39.50) <0.001 30(7.01–128.35) <0.001 26.95(6.14–118.23) <0.001
Without skin injuries 2.74(1.55–4.86) 0.001 2.06(0.99–4.27) 0.052 1.66(0.92–3.00) 0.090 1.57(0.85–2.91) 0.152
Eating any “high risk” dish in the last 2 weeks 3.25(2.02–5.24) <0.001 2.48(1.35–4.52) 0.003 6.00(3.33–10.81) <0.001 4.38(2.72–8.08) <0.001
Ill pigs at home in the last 4 weeks (4) 24.62(2.85–212.24) 0.004 30.10(2.72–333.64) 0.006 - - - -
Pigs at home with S. suis serotype 2 (confirmed by PCR) (5) 2.31(0.49–10.82) 0.289 7.83(0.68–90.19) 0.099 - - - -
(1)

Crude OR based on logistic (hospital controls) or conditional logistic regression (community controls).

(2)

Adjusted for age, sex and rural/urban residence, using logistic regression.

(3)

Adjusted for sex (matched for age and residence), using conditional logistic regression.

(4)

Only individuals with pigs at home were analyzed. OR could not be analyzed for community controls because none of them reported ill pigs at home.

(5)

Only individuals who had pig swab samples at their houses were analyzed. OR could not be analyzed for community controls because there was no discordant pairs included in the analysis.