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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Cancer. 2010 Nov 8;117(8):1630–1639. doi: 10.1002/cncr.25724

Figure 1. The miRNAs significantly up- or down-regulated in malignant and/or benign adrenocortical tumors as compared to normal adrenocortical tissue.

Figure 1

Microarray analysis compared tumors (benign or malignant) to normal adrenocortical tissue. Differentially expressed genes were defined as those that had a p-value <0.01 (Ho: there is no difference between expression in tumor and normal). 17 miRNAs were misexpressed in both benign and malignant tumors (listed in the box, green and red indicate lower and higher expression in tumors, respectively). The underlined miRNAs were chosen to be validated by real-time quantitative RT-PCR.