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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Free Radic Biol Med. 2011 Jan 14;50(8):945–952. doi: 10.1016/j.freeradbiomed.2011.01.010

Fig. 6. Rieske iron-sulfur protein silencing inhibits HPV and hypoxic increase in [Ca2+]i in PASMCs.

Fig. 6

(A) Representative Western blots show Rieske iron-sulfur protein expression in PAs untransfected (control) and transfected with Rieske iron-sulfur protein siRNAs by reverse permeabilization. Bar graph summarizes the effect of Rieske iron-sulfur protein and scrambled siRNAs on Rieske iron-sulfur protein expression levels. (B) A representative recording illustrates hypoxic vasoconstriction in an isolated pulmonary artery. Graph shows the effect of Rieske iron-sulfur protein silencing on HPV. (C) Effect of Rieske iron-sulfur protein silencing on the hypoxic increase in [Ca2+]i in PASMCs. The Number in parenthesis indicates the number of independent experiments performed from 3 separate preparations.