Table 2.

GNP concentrations per gram of organ, tissue or blood: 24 h retention/accumulation of intravenously injected GNP (1.4nm, 5nm, 18nm, 80nm, 200mm coated with TPPMS; 2.8nm carboxyl- and amino-coated); GNP concentrations are given as percentages of initial dose. Data are mean ± SD, n = 4 rats.

198Au-GNP	1.4 nm	5 nm	18 nm	80 nm	200 nm	2.8 nm COO−	2.8 nm NH3+
Liver	5.1 × 100 ± 4.8 × 10−1	1.0 × 10+1 ± 2.2 × 10−1	1.0 × 10+1 ± 1.1 × 100	1.1 × 10+1 ± 1.3 × 100	1.2 × 10+1 ± 1.3 × 100	9.2 × 100 ± 2.7 × 10−1	7.9 × 100 ± 4.8 × 10−1
Spleen	2.3 × 100 ± 2.4 × 10−1	2.7 × 100 ± 1.2 × 100	1.6 × 100 ± 3.8 × 10−1	1.9 × 100 ± 5.2 × 10−1	3.6 × 100 ± 5.6 × 10−1	8.9 × 100 ± 1.9 × 100	1.3 × 101 ± 1.4 × 100
Lungs	2.0 × 10−1 ± 1.4 × 10−1	3.5 × 10−2 ± 5.1 × 10−3	3.8 × 10−2 ± 1.3 × 10−2	2.7 × 10−2 ± 1.1 × 10−2	3.7 × 10−2 ± 1.4 × 10−2	1.2 × 100 ± 3.4 × 10−1	1.2 × 100 ± 9.2 × 10−2
Kidneys	1.9 × 100 ± 2.8 × 10−1	3.7 × 10−2 ± 1.0 × 10−2	1.3 × 10−2 ± 4.5 × 10−3	1.6 × 10−2 ± 1.3 × 10−2	2.5 × 10−3 ± 3.2 × 10−3	4.0 × 10−1 ± 2.8 × 10−2	4.8 × 10−1 ± 2.9 × 10−2
Heart	1.8 × 10−1 ± 5.4 × 10−3	6.9 × 10−3 ± 2.3 × 10−3	9.4 × 10−3 ± 3.5 × 10−3	3.4 × 10−3 ± 2.0 × 10−3	5.6 × 10−3 ± 2.2 × 10−3	3.9 × 10−2 ± 1.6 × 10−3	5.2 × 10−2 ± 1.6 × 10−3
Brain	6.4 × 10−3 ± 1.2 × 10−3	6.0 × 10−5 ± 4.3 × 10−5	3.1 × 10−5 ± 3.7 × 10−5	2.9 × 10−4 ± 6.8 × 10−5	2.1 × 10−5 ± 2.3 × 10−5	1.8 × 10−3 ± 4.0 × 10−4	2.8 × 10−3 ± 2.2 × 10−4
Uterus	1.8 × 10−1 ± 5.1 × 10−2	7.9 × 10−3 ± 1.2 × 10−3	3.7 × 10−3 ± 1.8 × 10−3	1.5 × 10−3 ± 7.5 × 10−4	1.2 × 10−3 ± 3.8 × 10−4	2.6 × 10−2 ± 2.8 × 10−3	3.2 × 10−2 ± 5.1 × 10−3
Remainder	3.5 × 10−1 ± 2.1 × 10−2	7.7 × 10−3 ± 1.6 × 10−3	5.9 × 10−3 ± 3.0 × 10−3	1.6 × 10−2 ± 6.6 × 10−3	2.6 × 10−2 ± 9.4 × 10−3	2.2 × 10−2 ± 1.1 × 10−3	4.4 × 10−2 ± 2.6 × 10−3
Blood	1.1 × 10−1 ± 6.0 × 10−3	2.4 × 10−2 ± 3.6 × 10−3	1.6 × 10−2 ± 6.6 × 10−3	1.6 × 10−3 ± 5.0 × 10−4	8.6 × 10−4 ± 6.0 × 10−4	1.1 × 10−1 ± 3.0 × 10−3	9.5 × 10−2 ± 5.2 × 10−3