Table 1.

Outcomes of make-and-test applications of topomer CoMFA by four discovery organizations

Ref.	TopCoMFA model properties					Make-&-test outcomes
	q2	SD	# Comp	N	pIC50 range	# Predicted	pIC50 SDEP	N top pIC50 quartile
[9]	0.220	0.66	3	122	3.3–7.3	7	0.54	2
[10]	0.593	0.49	8	270	4.2–8.8	2	0.36	2
[11]	0.518	0.63	5	358	NA	44	0.69	Most
NA	0.342	0.95	7	206	4.3–8.0	87	0.48	19
Total/Average						140	0.51

See text for explanation