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. Author manuscript; available in PMC: 2011 Mar 9.
Published in final edited form as: World Rev Nutr Diet. 2010 Apr 30;101:34–45. doi: 10.1159/000314509

Table II.

Meat mutagen XME gene pathways in relation to advanced colorectal adenoma.

Meat Mutagen Genes P valuea
HCAs CYP1A1, NAT1, NAT2, SULT1A1, SULT1A2 0.312
PAHs CYP1A1, CYP1B1, CYP3A4, EPXH, GSTM1, GSTP1, GSTT1, NQO1, SULT1A1, SULT1A2 0.172
NOCs CYP2A6, CYP2C9, CYP2E1, GSTM1, GSTT1, GSTP1, NAT1, NAT2, NQO1 0.225
a

Global pathway test based on inclusion of all SNPs for a given pathway compared to a model without any SNPs.