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. 2011 Mar;162(5):1136–1142. doi: 10.1111/j.1476-5381.2010.01110.x

Figure 3.

Figure 3

Perfusion of hearts with N,N,N′,N′-tetramethylphenylene-1,4-diamine (TMPD) did not prevent ischaemia-induced inhibition of mitochondrial respiration. Hearts were pre-perfused for 15 min with 50 µM TMPD prior to induction of stop-flow ischaemia. Mitochondrial respiration was measured using 1 mM pyruvate plus 1 mM malate as substrates. State 3 respiration rate was obtained by the addition of 1 mM ADP. *Statistically significant effect if compared with control (P < 0.01). Means ± SE of 4–9 separate experiments are presented.