Table 2. Tajima's D and Ewens-Watterson (EW) tests of selective neutrality at each of the seven HLA loci analyzed.
Tajima | |||||
Locus | n | D<0a | %b | D>0a | %b |
A | 97 | 0 (0) | 0 (0) | 86 (5) | 88.7 (5.2) |
B | 90 | 0 (0) | 0 (0) | 87 (5) | 96.7 (5.6) |
Cw | 68 | 0 (0) | 0 (0) | 57 (1) | 83.8 (1.47) |
DRB1 | 106 | 0 (0) | 0 (0) | 98 (12) | 92.5 (11.3) |
DQA1 | 58 | 0 (0) | 0 (0) | 54 (38) | 93.1 (65.5) |
DQB1 | 89 | 1 (0) | 1.1 (0) | 72 (18) | 80.9 (20.2) |
DPB1 | 56 | 2 (1) | 3.6 (1.8) | 36 (3) | 64.3 (5.4) |
n: number of populations.
: number of significant outcomes at the 5% level, and after Bonferroni's correction for multiple tests within brackets.
: proportion of significant outcomes at the 5% level, and after Bonferroni's correction for multiple tests within brackets.