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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Otol Neurotol. 2010 Dec;31(9):1391–1398. doi: 10.1097/MAO.0b013e3181f6c899

Table 1.

Patterns of electrophysiologic changes with associated intracochlear damage of all 16 animals and 18 ears tested. Two animals underwent bilateral testing (animals #74 and 76). The table categorizes the cases into three types of tracks observed based on physiological patterns (see also Figure 3).The categories are based on changes in the CM, because the CAP was typically stable. The categories were early, irreversible loss of CM, or loss seen unrelated to the advancement of the electrode; late, irreversible loss of CM, or a reduction in the CM that occurred only after electrode advancement and did not recover on electrode retraction; and reversible loss of the CM, where the CM recovered when the electrode was retracted. In some of the RCM cases, after the reversibility was demonstrated the electrode was further advanced until the change became irreversible. Also indicated are the structure impacted and degree of damage

Classification Animal Physiology Histology
Pattern Description # Ear CM CAP Structure Description
#1 Early irreversible decrease of CM CAP changes 47 right I I BM/OSL Full thickness
38 right I I BM/OSL Full thickness
72 right I I BM/OSL Full thickness
69 right I I BM Full thickness

CAP stable 74 left I S BM Full thickness

#2 Irreversible CM decrease, CAP stable 65 right I S OSL Superficial
76 left I S OSL/BM Superficial
67 right I S OSL Superficial
29 right I S OSL Superficial
36 right I S BM Full thickness

#3 Reversible CM decrease 41 right R S NA Absent trauma
64 right R S OSL Superficial
71 right R S OSL Superficial

Reversible, then irreversible CM
decrease
CAP stable 58 right R/I S OSL Superficial
76 right R/I S OSL Superficial
74 right R/I S BM Superficial
56 right R/I S OSL Superficial

CAP changes 31 right R/I R/I BM Full thickness

Abbreviations: I: irreversible change, R: reversible change, R/I: reversible change, then irreversible change, S: stable.