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. 2011 Mar 7;192(5):711–721. doi: 10.1083/jcb.201010129

Figure 1.

Figure 1.

Chromosome conformation and transcriptional activity are affected by the association of chromosomal regions with peripheral or central subcompartments. (a) The nuclear lamina and adjacent nuclear space, (b) nuclear pore complexes, (c) a nucleolus, where ribosomal DNA loci from different chromosomes cluster, (d) a transcription factory, where coregulated genes preferentially colocalize, and (e) a polycomb body. The filled gray region represents a CT that is interacting with both a and c.