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Localisation of CRH immunostaining in the sebaceous gland of acne patients (A) and in the normal skin of healthy controls (B). Very intensive expression of the gene in all types of sebocytes—basal, differentiating and mature cells—and keratinocytes of ductus seboglandularis in acne skin is shown (A) (x400); significant weaker and dependent upon sebocytes differentiation stage immunoreaction of sebaceous gland in normal skin (B) (x400).
