Table 3.
Relative risk of second primary cancer by type of first primary cancer and age group at first diagnosis, Queensland, 1982-2006
| Age group at first diagnosis | ||||||
|---|---|---|---|---|---|---|
| 15-49 years | 50-64 years | 65 years and over | ||||
| First primary cancer | Obs. |
SIR (95% CI) |
Obs. |
SIR (95% CI) |
Obs. |
SIR (95% CI) |
| Head and neck | 223 |
2.07 (1.80-2.36) |
884 |
2.20 (2.06-2.35) |
882 |
1.77 (1.65-1.89) |
| Oesophagus | 6 |
4.00 (1.47-8.70) |
39 |
1.70 (1.21-2.32) |
60 | 1.16 (0.88-1.49) |
| Stomach | 17 | 1.59 (0.93-2.55) |
60 | 1.04 (0.79-1.34) |
129 | 0.91 (0.76-1.08) |
| Colorectal | 188 |
1.58 (1.36-1.82) |
994 |
1.15 (1.08-1.22) |
1,864 | 1.03 (0.99-1.08) |
| Pancreas | -- | -- | 26 |
1.60 (1.05-2.35) |
23 |
0.61 (0.39-0.92) |
| Lung | 52 |
2.46 (1.84-3.23) |
270 |
1.55 (1.37-1.74) |
407 |
1.24 (1.12-1.36) |
| Melanoma | 1,121 |
2.05 (1.94-2.18) |
1,755 |
1.80 (1.72-1.89) |
2,216 |
1.74 (1.67-1.81) |
| Breast - female | 689 |
1.86 (1.72-2.00) |
1,047 |
1.29 (1.21-1.37) |
1,226 |
1.15 (1.08-1.21) |
| Cervix | 129 |
1.33 (1.11-1.57) |
94 |
1.49 (1.21-1.83) |
77 |
1.27 (1.01-1.59) |
| Uterus | 47 |
1.63 (1.20-2.17) |
164 | 1.07 (0.91-1.25) |
198 |
1.16 (1.00-1.33) |
| Ovary | 33 | 1.25 (0.86-1.76) |
64 | 1.12 (0.87-1.44) |
67 | 1.06 (0.82-1.34) |
| Prostate | 7 | 0.81 (0.32-1.66) |
554 |
0.87 (0.80-0.95) |
2,445 |
0.82 (0.79-0.85) |
| Kidney | 52 |
1.63 (1.22-2.14) |
230 |
1.59 (1.39-1.81) |
373 |
1.57 (1.42-1.74) |
| Bladder | 81 |
2.02 (1.60-2.51) |
465 |
1.63 (1.49-1.79) |
1,134 |
1.70 (1.60-1.80) |
| Brain & CNS | 27 |
1.64 (1.08-2.39) |
15 | 0.94 (0.52-1.55) |
8 |
0.48 (0.21-0.95) |
| Thyroid | 65 | 1.22 (0.94-1.55) |
84 |
1.39 (1.11-1.72) |
66 |
1.37 (1.06-1.74) |
| Non-Hodgkin lymphoma | 81 |
1.60 (1.27-1.99) |
261 |
1.57 (1.39-1.77) |
347 |
1.23 (1.10-1.36) |
| Lymphoid leukaemia | 27 |
2.68 (1.77-3.90) |
131 |
1.69 (1.42-2.01) |
264 |
1.57 (1.39-1.77) |
| Myeloid leukaemia | 22 |
2.23 (1.40-3.38) |
33 | 1.39 (0.96-1.95) |
70 |
1.35 (1.05-1.70) |
| Myeloma/PCT | 8 | 1.40 (0.61-2.77) |
47 | 1.35 (0.99-1.79) |
79 | 0.89 (0.70-1.10) |
| Other | 273 |
1.69 (1.49-1.90) |
472 |
1.43 (1.30-1.56) |
808 |
1.20 (1.12-1.29) |
| All cancers combined | 3,150 |
1.84 (1.77-1.90) |
7,687 |
1.39 (1.36-1.42) |
12,743 |
1.23 (1.20-1.25) |
Obs. = Observed number of second primary cancers; SIR = standardised incidence ratio; CI = confidence interval; CNS = central nervous system; PCT = plasma cell tumours. SIRs shown in normal bold font indicate significantly increased risk; SIRs shown in bold italics indicate significantly decreased risk. SIRs for pancreatic cancer for the age groups 15-49 years and 50-64 years have been combined due to less than 5 observed cases aged 15-49 years.