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. 2011 Jan 1;5(1):23–33. doi: 10.4161/chan.5.1.13905

Figure 2.

Figure 2

Residue conservation patterns from multiple sequence alignments, used as a modeling criteria. (A) Target-template sequence alignment in which residues are highlighted according to their degree of conservation, on a scale from red (highly conserved) to blue (not conserved). (B) Top view and (C) bottom view of the models for closed (left), low-conductive (center) and open (right) conformations, colored according to the same degree-of-conservation scheme.