Table 1.

Peak currents obtained with WT and Δ76–125 TREK-1 in two recording configurations

	Cell-attached patches	Excised inside-out patches
WT	600 ± 370 pA, (n = 8)	520 ± 300 pA, (n = 9)
Δ76–125	55 ± 30 pA, (n = 10)	65 ± 40 pA (n = 6)
t-test	p < 0.002	p < 0.004

The currents were recorded under −40 mV command voltage in response to pressure pulses that patches could sustain with standard pipettes pulled to BN5.