Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) Ionic and gating currents of hNaV1.4 in the cut-open configuration in response to 0 mV depolarization for control (left), 500 nM anthopleurin (middle) or 2 µM tetrodotoxin (right). Parameters for conductance, charge movement and its immobilization were obtained from Boltzmann fits to normalized curves as shown in (B and C). Values represent mean ± SEM for 16 to 34 experiments. Calibration: vertical 400 nA; horizontal 10 ms.
