Table 2.
Blood and urine measurements after 1 week of diet as outpatient
| Before Meat (casein) Diet | After Meat (casein) Diet | Before Vegetarian (grain) Diet | After Vegetarian (grain) Diet | P (paired t test)a | |
|---|---|---|---|---|---|
| Average daily phosphorus intake (mg/day) | 810 ± 27 | 795 ± 51 | NS | ||
| Plasma phosphorus (mg/dl) | 3.5 ± 0.6 | 3.7 ± 0.6 | 3.5 ± 0.6 | 3.2 ± 0.5 | 0.02 |
| Plasma intact PTH (pg/ml) | 58 ± 31 | 46 ± 29 | 58 ± 39 | 56 ± 30 | 0.002 |
| Plasma FGF23 (pg/ml) | 72 ± 39 | 101 ± 83 | 84 ± 65 | 61 ± 35 | 0.008 |
| Plasma calcium (mg/dl) | 9.2 ± 0.4 | 9.4 ± 0.7 | 9.3 ± 0.4 | 9.1 ± 0.3 | NS |
| Creatinine clearance (ml/min) | 47 ± 16 | 47 ± 16 | 43 ± 11 | 44 ± 16 | NS |
| Urine 24-hour calcium excretion (mg/24 h) | 66 ± 69 | 77 ± 48 | 60 ± 59 | 71 ± 43 | NS |
| Urine 24-hour phosphorus excretion (mg/24 h) | 836 ± 187 | 583 ± 216 | 778 ± 190 | 416 ± 233 | 0.07 |
| Urine 24-hour FePhosph (%) | 38.0 ± 6.2 | 23.9 ± 5.1 | 38.2 ± 11.5 | 20.9 ± 9.9 | NS |
a
By paired t test comparing results at end (after) each 7-day controlled diet study period drawn at the same time (8:00 p.m.). Results are mean ± SD. The before values are shown to demonstrate what the patients ate on their own during the before-study and washout periods and to demonstrate no carryover effect.