Table 4.

Associations among copeptin, GFR, and ERBF as markers of disease severity in ADPKD

Model	Adjusted for	GFR		ERBF
		Standardized β	P	Standardized β	P
1	Crude	−0.58	<0.001	−0.52	<0.001
2	As 1 + age and gender	−0.55	<0.001	−0.55	<0.001
3	As 2 + use of diuretics	−0.53	<0.001	−0.54	<0.001

Independent variable is log copeptin. Dependent variables are GFR and ERBF (both in ml/min per 1.73 m²). A negative standardized β indicates that a high copeptin concentration is associated with a low GFR or ERBF.