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. 2011 Feb;32(1):5–31.

Figure 14.

Figure 14.

Method comparison between LC-MS/MS and immunoassay (Roche Cobas) measurement of PTH. (A) Scatterplot with regression fit and confidence intervals for slope and fit. (B) Bland-Altman plot showing percentage difference between methods plotted against the mean PTH of both methods. There is evidence for non-linearity of the difference, with the difference between the two assays first declining from a high percentage low bias for the immunoassay to a lesser percentage bias, and then to increasingly higher percentage biases for the immunoassays at very high PTH concentrations. Reprinted from Kumar et al. (Clin Chem 2010;56:306–13) with permission from Clinical Chemistry.