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The effects of BRC extracts on COX-1 and COX-2 activity
| PRODUCT | IC50 COX-2 (μg/ml) | IC50 COX-1 (μg/ml) | Activity Ratio (COX-2:COX-1) |
|---|---|---|---|
| BRC-301 | 1.8 ± 0.1 | 2.4 ± 0.2 | 0.75 |
| BRC-304 | 3.6 ± 0.8 | 33.5 ± 4.5 | 0.11 |
| BRC-306 | 0.07 ± 0.1 | 0.78 ± 0.1 | 0.09 |
The natural product formulations were evaluated via a COX enzyme activity assay and IC50 values are shown along with the corresponding activity ratio.
