Table 3.
Active principle | Brand name | Dosage and time of administration |
---|---|---|
Fondaparinux | ARIXTRA® |
2.5 mg at least 6 h after surgery, then 2.5 mg/daya If creatinine clearance 20–50 ml/min 1.5 mgb |
aIn agreement with the latest edition of the American College of Chest Physicians (ACCP) guidelines [1], initiation may be postponed up to 24 h after the end of the intervention [9], although this has not been included in the label as yet
bAccording to the recent guidelines of the European Society of Anaesthesiology [10], FON is contraindicated if creatinine clearance < 30 ml/min