. 2011 Jan 19;12(1):69–76. doi: 10.1007/s10195-010-0125-8

Table 5.

Correlation between anesthesia and antiplatelet treatment (APT)

Regional anesthesia^a	General anesthesia
Acetylsalicylic acid (ASA): do not interrupt in case of secondary prevention (75–100 mg/day)	Ticlopidine—interrupt 10 days pre-op	GA always feasible
IIb/IIIa inhibitors Abciximab—RA contraindicated Eptifibatide—interrupt 8 h pre-op Tirofiban—interrupt 4 h pre-op	Clopidogrel—interrupt 7 days pre-op	Risk of surgical bleeding must always be considered before surgery

Regional anesthesia^a

General anesthesia

Patients on APT with

Patients on APT

Acetylsalicylic acid (ASA): do not interrupt in case of secondary prevention (75–100 mg/day)

Ticlopidine—interrupt 10 days pre-op

GA always feasible

IIb/IIIa inhibitors

Abciximab—RA contraindicated

Eptifibatide—interrupt 8 h pre-op

Tirofiban—interrupt 4 h pre-op

Clopidogrel—interrupt 7 days pre-op

Risk of surgical bleeding must always be considered before surgery

^aAPT, if no bleeding occurs, must be resumed the day following the intervention and, in the presence of epidural catheterization, after catheter removal