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. 2009 Jan 1;340(1):11–24. doi: 10.1016/j.jim.2008.09.014

Table 1.

Affinity measurements of the interaction between the ILA1 TCR and hTERT540-548 pMHCI variants

LIGAND 8E 5Y 4L Index 8Y 3G8T 3G
KD ILA1 TCR Binding (μM) > 500 242 117 36.6 22.6 4.04 3.7

Summary of the results obtained by nonlinear analysis of surface plasmon resonance binding equilibrium experiments as detailed in (Laugel et al., 2007) and (Melenhorst et al., 2008). KD values were determined by analyzing the data in nonlinear curve fittings to the equation AB = B x ABmax / (KD + B) assuming 1:1 Langmuir binding.