Fig. 4.
Phylogenetic relationships of 5′ NTR of GB viruses and hepaciviruses. (a) 5′ NTR nucleotide sequences from GBV-Ccpz, GBV-C, HCV, GBV-A and GBV-B, and the sequences from chimpanzees P187 (HM638236), 1855 (HM626488), Candie (HM626490), 3912 (HM769722) and 3915 (HM626491) were aligned with clustal w. There are 308 nt in the final dataset, although only 137 nt were available for sequence alignment with 3912 (marked with an asterisk). (b) GBV-Ccpz 5′ NTR sequences from non-captive chimpanzees (noted in italics; see text) were included in the comparison. There are 98 nt in the final dataset except for 3912, for which there were 45 nt available. The evolutionary distances were computed using the maximum composite likelihood method. Bootstrap values are shown for each branch point. Scales indicate the number of base substitutions per site.