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. 2011 Mar;66(3):351–359. doi: 10.1111/j.1398-9995.2010.02483.x

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Copyright © 2011 John Wiley & Sons A/S

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Application of Staphylococcus aureus extracellular vesicles (EV) to tape-stripped mouse skin induces atopic dermatitis-like inflammation. (A) Study protocol: application of different doses of S. aureus EV to tape-stripped mouse skin for 4 weeks (n = 5 per treatment group). (B) Skin histology [H&E staining; magnification, ×200 (upper panel) and ×400 (lower panel)]. Arrowheads identify eosinophils. (C) Histological analysis of epidermal thickness and the numbers of eosinophils and mast cells infiltrating the dermis. *P < 0.05; **P < 0.01; ***P < 0.001.