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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Curr Opin Struct Biol. 2010 Dec 19;21(1):128–136. doi: 10.1016/j.sbi.2010.11.006

Figure 1.

Figure 1

Crystal structure of the RCC1-nucleosome complex (PDB: 3MVD). (a) Overview of RCC1-nucleosome complex shows that RCC1 uses loops and its N-terminal arm to engage the nucleosome. (b) RCC1 uses its switchback loop to bind to the histone dimer acidic patch and an adjacent DNA-binding loop to interact with nucleosomal DNA.