Figure 3.

From cells to circumstantiality: a unified model outlining (a) γ-aminobutyric acid (GABA)-ergic cellular abnormalities, (b) ‘micro-circuit' gamma oscillatory function, (c) regional recruitment of the prefrontal cortex (PFC) in mediating cognitive control, (d) engagement of the ‘macro-circuit', the coordinated activation of frontal and parietal regions as a neural system, (e) cognitive/behavioral performance on cognitive control tasks (eg, AX-Continuous Performance Task (AX-CPT) and Stroop), and (f) disorganization symptoms.