Skip to main content
. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Ann Neurol. 2011 Jan;69(1):141–151. doi: 10.1002/ana.22149

Figure 5. Quanitative analysis of HERV-K RT immunostaining in cortical brain tissue of patients with ALS or systemic disease.

Figure 5

Patients with ALS exhibit significantly more HERV-K RT protein expression, as measured by staining density, than cortical tissue from patients with systemic disease (Panel A). The same trend was evident when cell counting was used to quantify HERV-K RT expression (Panel C). As an experimental control, the Nissl to DAPI ratios demonstrate that there is similar neuronal staining in both ALS and patients with systemic disease (Panels B and D). Asterisk represents p<0.05.