Subjective ratings on a Visual Analogue Scale (0–100) are shown on the left ordinates and time (min) is shown on the abscissae. Points above BL were collected 10 min before drug administration at time 0. Each data point is the average (± S.E.M.) of five or six subjects. All other details are as described in the legend for Figure 8. Reprinted with permission from Mendelson, J.H., Sholar, M.B., Mutschler, N.H., Jaszyna-Gasior, M., Goletiani, N.V., Siegel, A.J. and Mello, N.K.: Effects of intravenous cocaine and cigarette smoking on luteinizing hormone, testosterone and prolactin in men. J. Pharmacol. Exp. Ther. 307:339–348, 2003.