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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Horm Behav. 2009 Oct 14;58(1):57–71. doi: 10.1016/j.yhbeh.2009.10.003

Figure 9. Luteinizing Hormone Levels after Cigarette Smoking or i.v. Cocaine Administration.

Figure 9

Plasma LH levels (mIU/ml) is shown on the abscissae. Points above BL were collected 10 min before drug administration at time 0. Each data point is the average (± S.E.M.) of six subjects. The top panel shows LH levels after smoking a high nicotine yield cigarette (filled circles) and a placebo cigarette (open circles). The 12 min cigarette-smoking period is indicated by the grey rectangle. The bottom panel shows LH levels after administration of 0.4 mg/kg, i.v. cocaine (closed circles) or placebo-cocaine. The vertical line indicates when cocaine or placebo-cocaine was administered. Asterisks indicate points that were significantly different from baseline (* = P< 0.05; ** = P< 0.01). Daggers indicate points at which LH was significantly different after high nicotine yield cigarette smoking than after placebo cigarette smoking, or when LH was significantly different after active cocaine than after placebo-cocaine († = P< 0.05; †† = P< 0.01). Reprinted with permission from Mendelson, J.H., Sholar, M.B., Mutschler, N.H., Jaszyna-Gasior, M., Goletiani, N.V., Siegel, A.J. and Mello, N.K.: Effects of intravenous cocaine and cigarette smoking on luteinizing hormone, testosterone and prolactin in men. J. Pharmacol. Exp. Ther. 307:339–348, 2003.