Table 1.
Study cohort demographic and clinical characteristics. Listed p-values are from univariate analysis.
| p-Value (Univariate Analysis) | ||
|---|---|---|
| Average Age (years) ± SD | 51.1 ± 14.7 | 0.0043 |
| Sex | 0.0075 | |
| Male | 282 | |
| Female | 59 | |
| Ethnicity | 0.0002 | |
| White | 211 | |
| Asian/Pacific Islander | 69 | |
| African American | 13 | |
| Other/Unknown | 48 | |
| Family History of Thyroid Malignancy | 47 | 0.069 |
| Prior History of Radiation* | 36 | 0.84 |
| NCI Classification on FNA Cytology (n = 423) | <0.0001 | |
| Benign | 181 | |
| Atypia of Undetermined Significance | 41 | |
| Neoplasm | 43 | |
| Suspicious for Malignancy | 13 | |
| Malignant | 78 | |
| Nondiagnostic | 2 | |
| Average Tumor Diameter (cm) ± SD | 2.8 ± 1.4 | 0.0015 |
| Number of Thyroid nodules in patients | 0.56 | |
| 1 nodule | 268 | |
| 2 nodules | 66 | |
| 3 nodules | 6 | |
| 4 nodules | 1 |
| * Prior History of Radiation | 36 |
|---|---|
| Treatment for Acne in childhood | 4 |
| Treatment for prior malignancy | 12 |
| Chernobyl Accident | 9 |
| Occupational Exposure | 7 |
| Radioiodide Treatment | 1 |
| Treatment for tuberculosis | 1 |
| Thymic irradiation as infant | 1 |
| Neck irradiation for persistent cough | 1 |
*
Specific type of prior history of radiation exposure