. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Best Pract Res Clin Haematol. 2010 Sep;23(3):391–401. doi: 10.1016/j.beha.2010.06.006

Table 4.

Commonly used surface marker combinations for detection of stem and multipotent progenitor cell populations in mice

Cell population	Marker combination	LT-HSC frequency [%]	Reference
Hematopoietic stem cells (LKS)	Lin-Kit+Sca1+	<10
Hematopoietic stem cells (SLAM)	CD150+CD244−CD48− CD150+CD41−CD48−	30 45	Kiel et al. 2005[62] Kiel et al. 2005[62]
LT-HSC	Lin-Kit+Sca1+Flk2-CD34−, or Lin-Kit+Sca1+Flk2- Thy1.1dim	22 20	Osawa et al. 1996[58] Spangrude et al. 1988[54], Kiel et al. 2005[62]
LT-HSC (“SLAM LKS”)	Lin-Kit+Sca1+CD150+CD48−	47	Kiel et al. 2005[62]
LT-HSC (“SLAM Flk2 LKS”)	Lin-Kit+Sca1+Flk2-CD48−	N/A	Yilmaz et al. 2006[64]
ST-HSC	Lin-Kit+Sca1+Flk2-CD34+, or Lin-Kit+Sca1+Flk2- Thy1.1dim	-	Osawa et al. 1996[58] Christensen et al. 2001[60]
HSPC (Hematopoietic stem and progenitor cells)	Lin-Kit+Sca1+Flk2-	-	Rasko et al. 1995[59]
Multipotent progenitors (MPP)	Lin-Kit+Sca1+Flk2+CD34+, or Lin-Kit+Sca1+Flk2+Thy1.1-	-	Christensen et al. 2001[60]
MPP (SLAM)	CD150-CD244+CD48−	-	Kiel et al, 2005[62]
Lymphoid-primed multipotent progenitors (LMPP)	Lin-Kit+Sca1+Flk2++	-	Adolfsson et al. 2001[61]