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A, cross-sections of aortas from wild-type (+/+) and mgN/mgN (−/−) embryos (E16.5), and randomly sacrificed newborn mice (P1, P10, and P14) were stained with H&E or Weigert for elastic fibers. B, aortas from E16.5 and P14 wild-type (+/+) and mgN/mgN mice immunostained for SMemb, an embryonic VSMC marker. Scale bar, 50 μm in both panels.
