Table 1.
Demographic data, biochemical characteristics, and liver stiffness scores of controls and biliary atresia patients.
| Variables | Controls (n = 20) |
BA Patients (n = 60) |
P-value |
|---|---|---|---|
| Age (years) | 10.1 ± 0.7 | 9.6 ± 0.7 | 0.1 |
| Gender (Female: Male) | 10:10 | 32:28 | 0.5 |
| BMI (kg/m2) | 18.5 ± 0.5 | 18.0 ± 0.6 | 0.5 |
| Albumin (g/dl) | - | 4.3 ± 0.1 | NA |
| Total bilirubin (mg/dl) | - | 2.7 ± 0.5 | NA |
| Direct bilirubin (mg/dl) | - | 2.2 ± 0.5 | NA |
| AST (IU/l) | - | 128.1 ± 11.2 | NA |
| ALT (IU/l) | - | 109.5 ± 10.7 | NA |
| ALP (IU/l) | - | 431.0 ± 28.0 | NA |
| Platelet count (103/mm3) | - | 162.7 ± 12.8 | NA |
| APRI | - | 3.0 ± 0.3 | NA |
| Adiponectin (μg/ml) | 11.1 ± 1.1 | 15.5 ± 1.1 | 0.03 |
| Hyaluronic acid (ng/ml) | 23.9 ± 1.5 | 50.3 ± 7.1 | 0.03 |
| Liver stiffness (kPa) | 5.1 ± 0.5 | 30.1 ± 3.0 | <0.001 |
The data was expressed as mean ± SEM. BA, biliary atresia; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; APRI, aspartate aminotransferase to platelets ratio index; NA, not applicable