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. Author manuscript; available in PMC: 2012 Mar 10.
Published in final edited form as: J Med Chem. 2011 Feb 14;54(5):1126–1139. doi: 10.1021/jm100912b

Figure 5.

Figure 5

Panels A-C: Dose-dependent effects of compounds 1 and 29-31 on renilla luciferase expressed by rPIV5-RL in HeLa cells (Panel A), on viability of HeLa cells after 24 h (Panel B), and on viability of NHBE cells after 40 h (Panel C). Viability of mammalian cells was measured by quantification of cellular ATP with firefly luciferase. Panel D: Examination of effects of compounds (0.5 μM) compared with Triton X-100 (1%) on replication of intracellular M. fortuitum bacteria in HeLa cells. Data are in triplicate or larger numbers of measurements. Standard errors of the mean are ≤ 20%.