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. 2011 Feb 25;11:86. doi: 10.1186/1471-2407-11-86

Figure 4.

Figure 4

GPR39 promotes cell mobility and invasion by inducing partial EMT and remodeling cytoskeleton. (A) Representatives of cell morphology of GPR39-expressing cells and Vec-30 cells (original magnification × 200). (B) Expressions of epithelial markers E-cadherin and mesenchymal markers fibronectin, N-cadherin, and vimentin, were compared by RT-PCR or Western blotting analysis between GPR39-expressing cells and Vec-30 cells. GAPDH was used as loading control. (C) Representative images of F-actin staining. Formation of lamellipodia (indicated by arrows) was stimulated by GPR39 compared to control cells (magnification × 400).